BioGaia Protectis PLUS Baby Probiotics Drops with Vitamin D, 10ml (Exp 10/27)

BioGaia Protectis PLUS Baby Probiotics Drops with Vitamin D is the next-generation baby drops that uniquely combine L. reuteri Protectis®— one of the world’s most researched probiotics** — with the new and patented L. reuteri BG-R46®. The proprietary combination of these two L. reuteri strains (L. reuteri BG-R46® and L. reuteri Protectis®) in BioGaia® Protectis® Plus results in additive probiotic effects. It’s expertly formulated to complement your baby's natural gut flora. Enhanced with 10µg of Vitamin D, this next-generation formula supports your baby’s daily nutritional needs, contributing to the normal function of the immune system and supporting normal growth and development of bones in children*.

• Minimum 200 million CFU
• A dual-strain probiotic supplement for babies with colic and fussy tummies
• The only probiotic brand with LongevityGuard® - no refrigeration needed
  
• Easy-to-use squeezable tube, just 5 drops once daily
  
• Suitable for breast- or bottle-fed babies
  
• 10µg of Vitamin D3, 200% of RI (Reference intake) in the UK
• Backed by 30+ years of scientific research, trusted by generations of parents
  
• 5 drops daily

Recommended for 0 months+

*Vitamin D contributes to the normal function of the immune system in children. **According to the number of articles, PubMed Apr 2025.

The next-generation baby drops

For generations, BioGaia® has supported families worldwide with trusted probiotic solutions.

Building on decades of research, BioGaia has advanced its scientific knowledge with L. reuteri Protectis® and the addition of new L. reuteri BG-R46®.

Formulated to complement your baby's natural gut flora and support immune health, this next-generation formula helps support calmer moments throughout the days and nights.

Proven to maintain probiotic viability 4 x longer

BioGaia® is the only probiotic brand featuring LongevityGuard®, our patented protective technology that guarantees the stability and quality of live L. reuteri Protectis® (Lactobacillus reuteri). Each daily dose provides 200 million live friendly bacteria, guaranteed. No refrigeration required for convenient, everyday use.

In head‑to‑head testing, formulas with LongevityGuard® technology have been shown to keep the probiotics viable for 24 months, while non‑protected probiotics fell below the CFU limit by month 6.

What is the new L. reuteri BG-R46?

BG‑R46®, is BioGaia’s new patented probiotic strain developed in collaboration with the Swedish University of Agricultural Sciences (SLU). We wanted to develop a strain that could be even more adapted to the gut than its mother-strain Protecitis® DSM 17938. BG-R46® has kept many of the important properties of DSM 17938, but comes with an optimised toolbox, designed for a strain designated for the infant gut.

Ingredients

Sunflower oil, L. reuteri Protectis®(L. reuteri DSM 17938), L. reuteri BG-R46®, fully hydrogenated rapeseed oil and Vitamin D3 (cholecalciferol). The package contains a white desiccant device for prolongation of shelf-life. This should not be consumed.

Recommended dose: 

Intended for full-term infants only.

5 drops once daily. One daily dose (five drops) contains a minimum of 200 million live L. reuteri and 10µg of Vitamin D, corresponding to 200% of RI (Reference Intake) in the UK.

Recommended daily dose should not be exceeded. This product should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.

How To Use

For babies, drops can be dispensed onto the breast, or added to breast milk or formula, and can also be dispensed on a sterile spoon.

1. Shake well for 10 seconds before each use to mix the bacteria culture with the oil.

2. To dispense the drops, tilt the bottle gently and give by a spoon.

3. Use 5 drops once daily.

No need to refrigerate. Store below 25°C.

Do not add drops to hot food, hot drinks or feed directly into the mouth from the bottle as this may reduce the quality of the product.

Storage: Store in a dry place, not above room temperature (max 25°C). Products should be kept out of reach of children.

More about L. reuteri BG-R46

A newly patented strain, Limosilactobacillus reuteri BG-R46®, has been published in the prestigious journal Beneficial Microbes. This next-generation strain will be featured in BioGaia's upcoming baby drops product.

The proprietary combination of these two L. reuteri strains (L. reuteri BG-R46^® and L. reuteri Protectis^®) in BioGaia^® Protectis^® Plus results in additive probiotic effects.

The L. reuteri BG-R46® strain has several enhanced probiotic features such as increased tolerance to bile, which allows the bacteria to thrive in the digestive tract, increased adenosine production which contributes to reduction of inflammation in the body, more potent immune modulation in a milk-rich environment which is common in babies, and increased induction of  melatonin production by intestinal cells.

Improved key features of L. reuteri BG-R46:

• Increased survival and activity in bile-rich environment (Ermann Lundberg et al 2025).
• Increased melatonin induction by intestinal cells in human gut organoids, influencing gut motility and possibly sleep (Forshee et al 2026, accepted for publication).
• Higher production levels of the anti-inflammatory compound adenosine (Pang et al 2022, Liu et al 2023).
• Better adaptation to the infant gut and more potent immune modulation in milk-rich environment (R.C. Daniel et al 2025).
• Improved membrane vesicle bioactivity such as protection of the intestinal epithelial barrier (Pang et al 2022).